The modifications of the level of 10 plasma proteins representing 90-95% in weight of total plasma proteins, were evaluated by means of the molecular interpretation of agarose gel electrophoresis of fresh plasma. The level of some proteins: pre-albumin (pre-Alb), α1-antitrypsin (α1-At), orosomucoid (α1-AG), α2-macroglobulin (α2-M), haptoglobin (Hp) and fibrinogen (Fibr) was also determined by means of radial immunodiffusion. The proteins which showed marked reduction of concentration were: pre-Alb, α1-AG and Hp; Alb, α-lipo and γ-globulins were reduced to a lesser extent; α1-At, Tf, C3 and Fibr. showed mild reduction, while the level of α2-M was within normal adult range. The increase of orosomucoid and, above all, of α2-M paralleled the gestation time.
Plasma proteins modifications in pre-term newborns / R. Moratti, G. Melzi D'Eril, G. Merlini, A. Colombo. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 66:4(1981 Oct), pp. 682-686.
Titolo: | Plasma proteins modifications in pre-term newborns | |
Autori: | MELZI D'ERIL, GIANLODOVICO (Secondo) | |
Settore Scientifico Disciplinare: | Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica | |
Data di pubblicazione: | ott-1981 | |
Rivista: | ||
Tipologia: | Article (author) | |
Appare nelle tipologie: | 01 - Articolo su periodico |