The results of a multicentric retrospective analysis of 265 liver resections for hepatocellular carcinoma in cirrhotic patients have been collected and assessed. Overall operative mortality was 9.1%. The actuarial 3-year survival was 46.5%. Better results were obtained in patients with encapsulated lesions and alphafetoprotein levels less than 400 ng/dl. Tumoral recurrence, which was the main cause of late death, was related to alphafetoprotein higher levels and to the type of surgery performed: tumorectomies with short tumour free margin had the highest recurrence rate. Results were significantly better in those centers where intraoperative ultrasonography was siste-matically employed.
Liver resection for hepatocellular carcinoma in cirrhotic patients / G. Gozzetti, L. Belli, L. Capussotti, C. Di Carlo, L. Gennari, A. Maffei Faccioli, A. Mazziotti, E. Opocher, G.P. Spina. - In: ITALIAN JOURNAL OF GASTROENTEROLOGY. - ISSN 0392-0623. - 24:2(1992), pp. 105-110.
Liver resection for hepatocellular carcinoma in cirrhotic patients
E. OpocherPenultimo
;
1992
Abstract
The results of a multicentric retrospective analysis of 265 liver resections for hepatocellular carcinoma in cirrhotic patients have been collected and assessed. Overall operative mortality was 9.1%. The actuarial 3-year survival was 46.5%. Better results were obtained in patients with encapsulated lesions and alphafetoprotein levels less than 400 ng/dl. Tumoral recurrence, which was the main cause of late death, was related to alphafetoprotein higher levels and to the type of surgery performed: tumorectomies with short tumour free margin had the highest recurrence rate. Results were significantly better in those centers where intraoperative ultrasonography was siste-matically employed.
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