We report that acute quinpirole injection reduces BDNF mRNA levels in the rat hippocampus both at 2 and 6 h after the administration. These results suggest that the neurotrophin expression may be inhibited by situations involving dopaminergic overactivity.

Decreased hippocampal BDNF expression after acute systemic injection of quinpirole / F. Fumagalli, R. Santero, M. Gennarelli, G. Racagni, M. Riva. - In: NEUROPHARMACOLOGY. - ISSN 0028-3908. - 40:7(2001), pp. 954-957. [10.1016/S0028-3908(01)00017-X]

Decreased hippocampal BDNF expression after acute systemic injection of quinpirole

F. Fumagalli;G. Racagni;M. Riva
2001

Abstract

We report that acute quinpirole injection reduces BDNF mRNA levels in the rat hippocampus both at 2 and 6 h after the administration. These results suggest that the neurotrophin expression may be inhibited by situations involving dopaminergic overactivity.
Dopamine D2 receptors; Neurotrophin
Settore BIO/14 - Farmacologia
NEUROPHARMACOLOGY
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/182846
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