Despite the number of technologies used, the diagnosis of perioperative myocardial infarction is still a challenge. Studies conducted in surgical series have demonstrated that cardiac troponins (cTns) have both a superior diagnostic sensitivity and specificity, compared with other traditional techniques, and an independent power to predict short- and long-term prognosis. Nevertheless, some points need to be clarified. They include the usefulness of cTns in patients with end-stage renal failure; the standardization of the cTns cut-off for the diagnosis of myocardial injury; the timing of postoperative blood samplings; the cost-effectiveness of a screening in asymptomatic patients; and the possible therapeutic strategies.

Perioperative myocardial infarction in noncardiac surgery: the diagnostic and prognostic role of cardiac troponins / S. Lucreziotti, C. Foroni, C. Fiorentini. - In: JOURNAL OF INTERNAL MEDICINE. - ISSN 0954-6820. - 252:1(2002 Jul), pp. 11-20-20. [10.1046/j.1365-2796.2002.01006.x]

Perioperative myocardial infarction in noncardiac surgery: the diagnostic and prognostic role of cardiac troponins

C. Fiorentini
2002

Abstract

Despite the number of technologies used, the diagnosis of perioperative myocardial infarction is still a challenge. Studies conducted in surgical series have demonstrated that cardiac troponins (cTns) have both a superior diagnostic sensitivity and specificity, compared with other traditional techniques, and an independent power to predict short- and long-term prognosis. Nevertheless, some points need to be clarified. They include the usefulness of cTns in patients with end-stage renal failure; the standardization of the cTns cut-off for the diagnosis of myocardial injury; the timing of postoperative blood samplings; the cost-effectiveness of a screening in asymptomatic patients; and the possible therapeutic strategies.
Cardiac risk stratification; Cardiac troponins; Myocardial infarction; Noncardiac surgery
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/182714
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