The transesterification of 2-substituted-1,4-butanediols 1a, 2a and 3a with vinyl acetate catalyzed by the Pseudomonas cepacia lipase in organic solvents affords preferentially the 1-acetate, the highest regioselectivity having been found for the epoxydiol 3a, which is enantioselectively resolved [86% ee for the unreacted (S)-(-)-3a].
REGIOSELECTIVITY AND ENANTIOSELECTIVITY OF PSEUDOMONAS-CEPACIA LIPASE IN THE TRANSESTERIFICATION OF 2-SUBSTITUTED-1,4-BUTANEDIOLS / P. FERRABOSCHI, P. GRISENTI, A. MANZOCCHI, E. SANTANIELLO. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 5:4(1994), pp. 691-698. [10.1016/0957-4166(94)80031-6]
REGIOSELECTIVITY AND ENANTIOSELECTIVITY OF PSEUDOMONAS-CEPACIA LIPASE IN THE TRANSESTERIFICATION OF 2-SUBSTITUTED-1,4-BUTANEDIOLS
P. FERRABOSCHIPrimo
;A. MANZOCCHIPenultimo
;E. SANTANIELLOUltimo
1994
Abstract
The transesterification of 2-substituted-1,4-butanediols 1a, 2a and 3a with vinyl acetate catalyzed by the Pseudomonas cepacia lipase in organic solvents affords preferentially the 1-acetate, the highest regioselectivity having been found for the epoxydiol 3a, which is enantioselectively resolved [86% ee for the unreacted (S)-(-)-3a].
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
