A series of racemic and optically active N-alkylidenesulphinamides has been prepared and their reduction by metal hydrides studied. The extent of asymmetric synthesis mainly depends on the nature of the reducing species; the best results (up to 92% of stereoselectivity) are obtained with alkoxy-lithium aluminium hydrides. A new, highly enantioselective synthesis of amines is described.

Asymmetric induction in the reduction of optically active N-alkylidenesulphinamides by metal hydrides. A new efficient enantioselective route to chiral amines / R. Annunziata, M. Cinquini, F. Cozzi. - In: JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. I. - ISSN 0300-922X. - :0(1982), pp. 339-343.

Asymmetric induction in the reduction of optically active N-alkylidenesulphinamides by metal hydrides. A new efficient enantioselective route to chiral amines

R. Annunziata;M. Cinquini;F. Cozzi
1982

Abstract

A series of racemic and optically active N-alkylidenesulphinamides has been prepared and their reduction by metal hydrides studied. The extent of asymmetric synthesis mainly depends on the nature of the reducing species; the best results (up to 92% of stereoselectivity) are obtained with alkoxy-lithium aluminium hydrides. A new, highly enantioselective synthesis of amines is described.
Settore CHIM/06 - Chimica Organica
JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. I
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/182384
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