2-O-β-D-Galactosylglycerol 1 was submitted to acylation using Pseudomonas cepacia or Candida antarctica lipases as catalysts and 2,2,2- trifluoroethyl esters of butanoic, hexanoic, octanoic or decanoic acid as acyl carriers. Taking advantage of the high diastereoselectivity and regioselectivity of the two enzymes, the 1-O-, 3-O-, 6'-O-acyl and the 1,6'- di-O-acylderivatives of 1 were obtained pure or in an appreciably enriched form.
Bioctive glycoglycerolipid analogues: an expeditious enzymatic approach to mono- and diesters of 2-O-beta-D-galactoglycerol / D. Colombo, F. Ronchetti, A. Scala, L. Toma. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 9:12(1998), pp. 2113-2119.
Titolo: | Bioctive glycoglycerolipid analogues: an expeditious enzymatic approach to mono- and diesters of 2-O-beta-D-galactoglycerol |
Autori: | COLOMBO, DIEGO RODOLFO (Primo) RONCHETTI, FIAMMA CLELIA VIRGINIA (Secondo) SCALA, ANTONIO (Penultimo) |
Settore Scientifico Disciplinare: | Settore BIO/10 - Biochimica |
Data di pubblicazione: | 1998 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0957-4166(98)00207-9 |
Appare nelle tipologie: | 01 - Articolo su periodico |