The BF3. OEt2 or LiClO4 catalyzed hetero Diels-Alder reaction of 1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene (Danishefsky's diene) with enantiomerically pure 4-formylazetidin-2-ones affords the corresponding cycloadducts in fair to good yields and in diastereoisomeric ratios of up to 98:2. (C) 1998 Elsevier Science S.A. All rights reserved.
Stereoselective synthesis of new beta-lactams by cyclocondensation of 1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene with 4-formyl substituted azetidinones / R. Annunziata, M. Benaglia, M. Cinquini, F. Cozzi, F. Montanari, L. Raimondi. - In: IL FARMACO. - ISSN 0014-827X. - 53:10-11(1998), pp. 629-633.
Titolo: | Stereoselective synthesis of new beta-lactams by cyclocondensation of 1-methoxy-3-(trimethylsilyloxy)-1,3-butadiene with 4-formyl substituted azetidinones |
Autori: | ANNUNZIATA, RITA MARIA (Primo) BENAGLIA, MAURIZIO (Secondo) RAIMONDI, LAURA MARIA (Ultimo) |
Settore Scientifico Disciplinare: | Settore CHIM/06 - Chimica Organica |
Data di pubblicazione: | 1998 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0014-827X(98)00077-9 |
Appare nelle tipologie: | 01 - Articolo su periodico |