Twelve children born to hepatitis C virus antibody GBV-C/HGV RNA positive mothers who acquired GBV-C/HGV infection by the vertical or perinatal route were studied. Most (91%) were persistently GBV-C/HGV RNA positive up to 12 months of age. Four out of six cases who acquired GBV- C/HGV alone had normal alanine amino transferase activities. Long lasting evidence of hepatocellular injury was detected only in children with GBV- C/HGV and hepatitis C virus and HIV coinfection.
|Titolo:||Outcome of mother to infant acquired GBV-C/HGV infection|
ZANETTI, ALESSANDRO REMO (Penultimo)
PRINCIPI, NICOLA (Ultimo)
|Parole Chiave:||Hepatitis virus infection; HIV; Mother to infant transmission|
|Settore Scientifico Disciplinare:||Settore MED/42 - Igiene Generale e Applicata|
|Data di pubblicazione:||1999|
|Appare nelle tipologie:||01 - Articolo su periodico|