(R)- and (S)-2-methyldecan-1-ol 3a has been prepared in > 98% enantiomeric excess (ee) by transesterification with vinyl acetate in chloroform in the presence of Pseudomonas fluorescens lipase. Oxidation of the alcohol 3a affords nearly optically pure 2-methyldecanoic acid 3b.
A chemoenzymatic synthesis of enantiomerically pure (R)- and (S)-2-methyldecan-1-ol / P. Ferraboschi, P. Grisenti, A. Manzocchi, E. Santaniello. - In: JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS. I. - ISSN 0300-922X. - :9(1992), pp. 1159-1161.
A chemoenzymatic synthesis of enantiomerically pure (R)- and (S)-2-methyldecan-1-ol
P. FerraboschiPrimo
;A. ManzocchiPenultimo
;E. SantanielloUltimo
1992
Abstract
(R)- and (S)-2-methyldecan-1-ol 3a has been prepared in > 98% enantiomeric excess (ee) by transesterification with vinyl acetate in chloroform in the presence of Pseudomonas fluorescens lipase. Oxidation of the alcohol 3a affords nearly optically pure 2-methyldecanoic acid 3b.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
