The synthetically useful chiral synthons R and S (4E)-2-methyl-4-hexen-1-ol (1a) can be prepared enantiomerically pure by an enantioselective transacetylation with vinyl acetate of racemic 1a in dichloromethane catalyzed by a lipase from Pseudomonas fluorescens (PFL).

Enzymatic synthesis of enantiomerically pure chiral synthons: Lipase-catalyzed resolution of (R / S, 4 E)-2-Methyl-4-hexen-l-ol / P. Ferraboschi, D. Brembilla, P. Grisenti, E. Santaniello. - In: SYNLETT. - ISSN 0936-5214. - :5(1991), pp. 310-312.

Enzymatic synthesis of enantiomerically pure chiral synthons: Lipase-catalyzed resolution of (R / S, 4 E)-2-Methyl-4-hexen-l-ol

P. Ferraboschi
Primo
;
E. Santaniello
Ultimo
1991

Abstract

The synthetically useful chiral synthons R and S (4E)-2-methyl-4-hexen-1-ol (1a) can be prepared enantiomerically pure by an enantioselective transacetylation with vinyl acetate of racemic 1a in dichloromethane catalyzed by a lipase from Pseudomonas fluorescens (PFL).
2-methyl-1,3-propanediol derivatives; esters; reagents
Settore BIO/10 - Biochimica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/181109
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