Background. Among cardiac tumors myxoma is the most common benign neoplasm. The aim of this study was to review our Institution’s 15-year experience with intracardiac myxoma. Methods. From 1985 through 2001, 38 patients (22 males, 16 females, mean age 57.06 ± 11.1, range 32-74 years) underwent surgical resection of a cardiac myxoma at our Institution. The tumor was located in the left atrium in 29 patients (76.3%), in the right atrium in 8 patients (21%), and in the right ventricle in 1 patient (2.6%). The duration of symptoms prior to surgery ranged from 2 to 30 days. None of the patients had a familial myxoma. The surgical approach comprised complete wide excision in all patients. The incidence of delayed death, thromboembolic complications, valve degeneration, recurrence and reoperation were reviewed and the Kaplan-Meier survival curve was elaborated. Results. There were no perioperative deaths. Three patients (7.9%) developed postoperative neurological sequelae: transient ischemic attacks in 2 patients (5.2%) and a stroke with persistent neurological deficit in 1 patient (2.6%). One patient (2.6%) required pacemaker implantation for complete atrioventricular block. An inferior myocardial infarction occurred in 1 patient (2.6%). During the follow-up, complete in 89.4% of the patients (34 out of 38 patients, mean 96.8 ± 68.4 months, range 1-218 months), there were 2 (5.8%) non-cardiac related deaths. All the patients underwent clinical examination and echocardiography at regular intervals (1 year): no neurological event was observed during the follow-up and 29 patients (90.6%) are in NYHA functional class I. At 15 years the eventfree rate is 85.2%. At 15 years the actuarial survival for the whole group is 92%. Conclusions. At present, the diagnosis of myxoma is easy to make and two-dimensional echocardiography plays a major role in this field. Surgery is the gold standard treatment and the clinical longterm results are excellent.
|Titolo:||Il mixoma cardiaco: risultati chirurgici e follow-up clinico a 15 anni|
ANTONA, CARLO (Ultimo)
|Parole Chiave:||Atrial mass; Cardiac surgery; Cardiac tumor; Echocardiography; Myxoma; Primary cardiac tumor.|
|Settore Scientifico Disciplinare:||Settore MED/23 - Chirurgia Cardiaca|
|Data di pubblicazione:||lug-2002|
|Appare nelle tipologie:||01 - Articolo su periodico|