B cells are known to play a key role in the pathogenesis of autoimmune disease. B lymphocyte activating factor (BAFF), a member of TNF family, promotes autoantibody production by increasing B cell survival and proliferation. Serum BAFF concentrations have been found to be increased in systemic lupus erythematosus, rheumatoid arthritis, and Sjogren's syndrome
Serum BAFF concentrations in patients with Graves' disease and orbitopathy before and after immunosuppressive therapy / G. Vannucchi, D. Covelli, N. Currò, D. Dazzi, A. Maffini, I. Campi, P. Bonara, C. Guastella, L. Pignataro, R. Ratiglia, P. Beck Peccoz, M. Salvi. - In: THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM. - ISSN 0021-972X. - 97:5(2012 May), pp. E755-E759. [10.1210/jc.2011-2614]
Serum BAFF concentrations in patients with Graves' disease and orbitopathy before and after immunosuppressive therapy
G. Vannucchi;D. Covelli;N. Currò;A. Maffini;I. Campi;P. Bonara;L. Pignataro;R. Ratiglia;P. Beck Peccoz;
2012
Abstract
B cells are known to play a key role in the pathogenesis of autoimmune disease. B lymphocyte activating factor (BAFF), a member of TNF family, promotes autoantibody production by increasing B cell survival and proliferation. Serum BAFF concentrations have been found to be increased in systemic lupus erythematosus, rheumatoid arthritis, and Sjogren's syndrome
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