The present investigation has examined the clinical benefits of tobramycin, polymyxin E and amphotericin therapy in the management of oral mucositis in children undergoing chemotherapy prior to bone marrow transplantation. Tobramycin, polymyxin E, and amphotericin reduced the degree of oral mucositis more than conventional therapy of diphenhydramine, Maalox, and local analgesic. While there was a statistically significant fall in the severity of the mucositis with tobramycin, polymyxin E and amphotericin, this was unlikely to be of practical benefit.

Local antimicrobial therapy of oral mucositis in paediatric patients undergoing bone marrow transplantation / E. Bondi, C. Baroni, A. Prete, M. Gatti, A. Carrassi, G. Lodi, S.R. Porter. - In: ORAL ONCOLOGY. - ISSN 1368-8375. - 33:5(1997 Sep), pp. 322-326. [10.1016/S1368-8375(97)00039-0]

Local antimicrobial therapy of oral mucositis in paediatric patients undergoing bone marrow transplantation

A. Carrassi;G. Lodi
Penultimo
;
1997

Abstract

The present investigation has examined the clinical benefits of tobramycin, polymyxin E and amphotericin therapy in the management of oral mucositis in children undergoing chemotherapy prior to bone marrow transplantation. Tobramycin, polymyxin E, and amphotericin reduced the degree of oral mucositis more than conventional therapy of diphenhydramine, Maalox, and local analgesic. While there was a statistically significant fall in the severity of the mucositis with tobramycin, polymyxin E and amphotericin, this was unlikely to be of practical benefit.
Antimicrobials; Chemotherapy; Mucositis; Oral
Settore MED/28 - Malattie Odontostomatologiche
http://ac.els-cdn.com/S1368837597000390/1-s2.0-S1368837597000390-main.pdf?_tid=8ca81faec17969d6c4839ad64f0be6c1&acdnat=1341315821_2fe0f5d6f4aa72d61b85459d2cbda7b2
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/178608
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 36
  • ???jsp.display-item.citation.isi??? 33
social impact