An efficient protocol for the 4 beta-acylamidation of the N-acylated glycals of Neu5Ac by using the corresponding N-perfluoroacylated congeners as key tools has been developed and applied to the synthesis of glycals combining the features of the molecules with antiviral properties.
Facile Diastereoselective Entry to 4 beta-Acylamidation of Neu5Ac2en Glycals Using Their N-Perfluoroacylated Congeners as Key Tools / P. Rota, I. Agnolin, P. Allevi, M. Anastasia. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2012:13(2012), pp. 2508-2510.
Titolo: | Facile Diastereoselective Entry to 4 beta-Acylamidation of Neu5Ac2en Glycals Using Their N-Perfluoroacylated Congeners as Key Tools |
Autori: | ROTA, PAOLA (Primo) AGNOLIN, IRENE SOFIA (Secondo) ALLEVI, PIETRO (Penultimo) ANASTASIA, MARIO (Ultimo) |
Parole Chiave: | sialic acid ; glycals ; diastereoselectivity ; Fluorine |
Settore Scientifico Disciplinare: | Settore BIO/10 - Biochimica |
Data di pubblicazione: | 2012 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/ejoc.201200151 |
Appare nelle tipologie: | 01 - Articolo su periodico |
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