The aim of this study was to evaluate whether reappearance of polymerase chain reaction (PCR) positivity for the Bcl-2/IgH translocation following a phase of molecular remission in autografted follicular lymphoma (FL) patients is always associated with reappearance of the original neoplastic clone.

Recurrence of Bcl-2/IgH polymerase chain reaction positivity following a prolonged molecular remission can be unrelated to the original follicular lymphoma clone / M. Ladetto, B. Mantoan, I. Ricca, M. Astolfi, D. Drandi, M. Compagno, S. Vallet, M. dell'Aquila, A. Alfarano, P. Rossatto, A. Rocci, U. Vitolo, P. Corradini, M. Boccadoro, C. Tarella. - In: EXPERIMENTAL HEMATOLOGY. - ISSN 0301-472X. - 31:9(2003 Sep), pp. 784-788. [10.1016/S0301-472X(03)00191-7]

Recurrence of Bcl-2/IgH polymerase chain reaction positivity following a prolonged molecular remission can be unrelated to the original follicular lymphoma clone

P. Corradini;C. Tarella
2003

Abstract

The aim of this study was to evaluate whether reappearance of polymerase chain reaction (PCR) positivity for the Bcl-2/IgH translocation following a phase of molecular remission in autografted follicular lymphoma (FL) patients is always associated with reappearance of the original neoplastic clone.
Gene Expression Regulation, Neoplastic ; Polymerase Chain Reaction ; Genes, bcl-2 ; Humans ; Lymphoma, Follicular ; Genes, Immunoglobulin ; Tumor Markers, Biological ; Recurrence ; Translocation, Genetic ; False Positive Reactions
Settore MED/15 - Malattie del Sangue
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/177667
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