A 8 year old, DSH, male castrated cat was presented for exfoliative dermatitis and symmetrical alopecia with erosions of facial mucocutaneous junctions. Systemic signs included rhinitis, dyspnea and weight loss. Hair microscopic examination, skin scrapings, Wood lamp examination, and fungal cultures were negative. The cat was FIV, FeLV, Calicivirus negative and Herpesvirus positive. Abdominal ultrasound was normal and no mediastinic masses were detected by thoracic X-rays but hypertrophic cardiomyopathy was diagnosed. Skin biopsies evidenced orthokeratotic hyperkeratosis and mild epidermal and follicular exocytosis of mature T lymphocytes. Cat's conditions worsened and after euthanasia necropsy was performed. Skin lesions had worsened and follicular miniaturization had developed. Additional findings were hepatic degeneration and cirrhosis, mediastinal epithelial lined cysts (lym-phoepithelial cysts) associated with adipose tissue, connective tissue and epithelial cells, all findings compatible with a thymic hamartoma (synonym hamartomatous thymoma). The correlation of mediastinal and skin lesions and of the hepatic changes with follicular miniaturization and atrophy are discussed.
|Titolo:||Un caso di dermatite desquamativa generalizzata associata a cisti linfoepiteliali mediastiniche ed amartoma timico in un gatto|
ROCCABIANCA, PAOLA (Ultimo)
|Parole Chiave:||Exfoliative dermatitis; Feline; Lymphoepithelial cysts; Thymic hamartoma|
|Settore Scientifico Disciplinare:||Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria|
Settore VET/08 - Clinica Medica Veterinaria
|Data di pubblicazione:||giu-2012|
|Appare nelle tipologie:||01 - Articolo su periodico|