Various amounts of carbon dioxide were removed through an extracorporeal membrane lung in spontaneously breathing lambs. The decrease in alveolar ventilation was proportional to the fraction of total carbon dioxide removed by the membrane lung. When extracorporeal CO2 removal approximated CO2 production (VCO2), alveolar ventilation almost ceased. Pulmonary ventilation can be controlled by extracorporeal carbon dioxide removal.

Control of breathing using an extracorporeal membrane lung / T. Kolobow, L. Gattinoni, T.A. Tomlinson, J.E. Pierce. - In: ANESTHESIOLOGY. - ISSN 0003-3022. - 46:2(1977 Feb), pp. 138-141. [10.1097/00000542-197702000-00012]

Control of breathing using an extracorporeal membrane lung

L. Gattinoni
Secondo
;
1977

Abstract

Various amounts of carbon dioxide were removed through an extracorporeal membrane lung in spontaneously breathing lambs. The decrease in alveolar ventilation was proportional to the fraction of total carbon dioxide removed by the membrane lung. When extracorporeal CO2 removal approximated CO2 production (VCO2), alveolar ventilation almost ceased. Pulmonary ventilation can be controlled by extracorporeal carbon dioxide removal.
Oxygen; animals ; extracorporeal circulation ; blood flow velocity ; ventilation-perfusion ratio ; sheep ; hydrogen-ion concentration ; hypoventilation ; tidal volume ; oxygenators membrane ; carbon dioxide
Settore MED/41 - Anestesiologia
http://journals.lww.com/anesthesiology/pages/articleviewer.aspx?year=1977&issue=02000&article=00012&type=abstract
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/176733
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