Hepatitis C virus (HCV) infection is often associated with cryoglobulinaemia (CG). Peripheral neuropathy (PN) is a comparatively common complication of CG associated with HCV infection and it is thought to be attributable to nerve ischaemia. Only few HCV CG patients with PN have been reported. The recent finding of HCV RNA in nerve biopsy specimens has suggested a possible direct role of HCV in the pathogenesis of PN. The authors studied 51 HCV patients to determine the prevalence of CG and to clarify the possible mechanism by which HCV determines the PN.

Peripheral neuropathy in hepatitis C virus infection with and without cryoglobulinaemia / R. Nemni, L. Sanvito, A. Quattrini, G. Santuccio, M. Camerlingo, N. Canal. - In: JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY. - ISSN 0022-3050. - 74:9(2003 Sep), pp. 1267-1271.

Peripheral neuropathy in hepatitis C virus infection with and without cryoglobulinaemia

R. Nemni
Primo
;
2003

Abstract

Hepatitis C virus (HCV) infection is often associated with cryoglobulinaemia (CG). Peripheral neuropathy (PN) is a comparatively common complication of CG associated with HCV infection and it is thought to be attributable to nerve ischaemia. Only few HCV CG patients with PN have been reported. The recent finding of HCV RNA in nerve biopsy specimens has suggested a possible direct role of HCV in the pathogenesis of PN. The authors studied 51 HCV patients to determine the prevalence of CG and to clarify the possible mechanism by which HCV determines the PN.
Hepacivirus ; Peripheral Nervous System Diseases ; Humans; Cryoglobulinemia ; Prognosis ; Aged; Middle Aged ; Biopsy ; Hepatitis C ; Male ; Female
Settore MED/26 - Neurologia
Settore MED/17 - Malattie Infettive
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/176590
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