The synthesis of a series of 2-phenyl-1,4-benzodioxanes is reported. One of them, 2-(3-hydroxy-4-methoxyphenyl)-1,4-benzodioxane, is 450 times sweeter than sucrose, with an aftertaste similar to that of Phyllodulcin. Like this latter and other analogues, it satisfies the requirements of the Temussi sweet taste receptor model.

Synthesis and sweet taste of some 2-phenylbenzodioxanes / A. Arnoldi, L. Camarda, L. Merlini. - In: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. - ISSN 0021-8561. - 34:2(1986), pp. 339-344. [10.1021/jf00068a047]

Synthesis and sweet taste of some 2-phenylbenzodioxanes

A. Arnoldi
Primo
;
L. Merlini
Ultimo
1986

Abstract

The synthesis of a series of 2-phenyl-1,4-benzodioxanes is reported. One of them, 2-(3-hydroxy-4-methoxyphenyl)-1,4-benzodioxane, is 450 times sweeter than sucrose, with an aftertaste similar to that of Phyllodulcin. Like this latter and other analogues, it satisfies the requirements of the Temussi sweet taste receptor model.
Settore CHIM/10 - Chimica degli Alimenti
1986
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/176121
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