The physiological response to infections and injuries involves local inflammation and the initiation of events leading to a systemic response, also called acute phase reaction (APR). This multiplicity of changes is distant from the site of injury, and includes fever, leukocytosis and quantitative and qualitative modification of a group of non-structurally related proteins present in blood and other biological fluids, collectively named Acute Phase Proteins (APP). Proteomic investigations of serum or plasma following natural or experimental infection frequently reveal substantial alterations in the APP, several of which are high abundance proteins in these fluids. The present review will focus on the results of recent research on ruminant APP. Highlight points will include: This article is part of a Special Issue entitled: "Farm animal proteomics".

Acute phase proteins in ruminants / F. Ceciliani, J.J. Ceron, P.D. Eckersall, H. Sauerwein. - In: JOURNAL OF PROTEOMICS. - ISSN 1874-3919. - 75:14(2012 Jul 19), pp. 4207-4231.

Acute phase proteins in ruminants

F. Ceciliani
Primo
;
2012

Abstract

The physiological response to infections and injuries involves local inflammation and the initiation of events leading to a systemic response, also called acute phase reaction (APR). This multiplicity of changes is distant from the site of injury, and includes fever, leukocytosis and quantitative and qualitative modification of a group of non-structurally related proteins present in blood and other biological fluids, collectively named Acute Phase Proteins (APP). Proteomic investigations of serum or plasma following natural or experimental infection frequently reveal substantial alterations in the APP, several of which are high abundance proteins in these fluids. The present review will focus on the results of recent research on ruminant APP. Highlight points will include: This article is part of a Special Issue entitled: "Farm animal proteomics".
Acute phase protein; Adipose tissue; Disease diagnosis; Mammary gland; Protein function and expression; Ruminants
Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria
19-lug-2012
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/173840
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