Purpose. Farming is associated with a wide variety of hazardous exposures including physical, chemicals and biological agents. Animal farmers are exposed to dust which contains microorganisms, mycotoxins, endotoxins, animal feed particles, allergens and chemical agents. Organic dust exposure is known to cause allergic and non-allergic rhinitis, and organic dust toxic syndrome. This study was undertaken to evaluate the relationship between occupational health hazards and serum pro-inflammatory cytokines among agricultural workers, in particular we investigated whether animal breeders react differently to biological agents than non breeder farmers. Methods. One hundred subjects working in agricultural enterprises in the region of Lombardy, were enrolled into the study in 2010. Serum cytokines including interleukin (IL)-6, IL-8, IL-10, IFNγ and tumor necrosis factor-α (TNFα) were measured. Cytokines were assessed by commercially available enzyme-linked-immunosorbent assay (ELISA). Results of the study. Compared to control subjects, increased TNF-α, IL-8, and IL-10 levels were found in animal breeders, and a statistically significant relationship between type of job (breeder/non breeder workers) and increased serum pro-inflammatory cytokines. Results suggest that animal breeders might be at higher risk of occupational diseases and biological hazards than other farmers with less contact to animals.

Immunologic status of agricultural workers in the region of Lombardy, Northern Italy / G. Rabozzi, E. Corsini, M. Sokooti, R. Tabibi, C. Somaruga, F. Vellere, G. Brambilla, C. Colosio. ((Intervento presentato al convegno International Congress on Tracing New Occupational Diseases : Methodology, recent findings and implications for OHS-policy tenutosi a Amsterdam nel 2011.

Immunologic status of agricultural workers in the region of Lombardy, Northern Italy

G. Rabozzi;E. Corsini;R. Tabibi;C. Somaruga;F. Vellere;G. Brambilla;C. Colosio
2011-04-07

Abstract

Purpose. Farming is associated with a wide variety of hazardous exposures including physical, chemicals and biological agents. Animal farmers are exposed to dust which contains microorganisms, mycotoxins, endotoxins, animal feed particles, allergens and chemical agents. Organic dust exposure is known to cause allergic and non-allergic rhinitis, and organic dust toxic syndrome. This study was undertaken to evaluate the relationship between occupational health hazards and serum pro-inflammatory cytokines among agricultural workers, in particular we investigated whether animal breeders react differently to biological agents than non breeder farmers. Methods. One hundred subjects working in agricultural enterprises in the region of Lombardy, were enrolled into the study in 2010. Serum cytokines including interleukin (IL)-6, IL-8, IL-10, IFNγ and tumor necrosis factor-α (TNFα) were measured. Cytokines were assessed by commercially available enzyme-linked-immunosorbent assay (ELISA). Results of the study. Compared to control subjects, increased TNF-α, IL-8, and IL-10 levels were found in animal breeders, and a statistically significant relationship between type of job (breeder/non breeder workers) and increased serum pro-inflammatory cytokines. Results suggest that animal breeders might be at higher risk of occupational diseases and biological hazards than other farmers with less contact to animals.
farm workers ; swine breeders ; inflammatory cytokines ; biological risks
Settore MED/44 - Medicina del Lavoro
Scientific Committee on Occupational Medicine (SCOM) of the International Commission on Occupational Health (ICOH)
Netherlands Center of Occupational Diseases (NCOD)
University of Amsterdam
http://www.icohscom2011.nl/content/program-presentations
Immunologic status of agricultural workers in the region of Lombardy, Northern Italy / G. Rabozzi, E. Corsini, M. Sokooti, R. Tabibi, C. Somaruga, F. Vellere, G. Brambilla, C. Colosio. ((Intervento presentato al convegno International Congress on Tracing New Occupational Diseases : Methodology, recent findings and implications for OHS-policy tenutosi a Amsterdam nel 2011.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/172341
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