Toxic metals are involved in the pathogenesis of some neurodegenerative and vascular diseases and are known to impair the immune system functions. We report here the case of a patient affected by heavy metal intoxication, who had developed an autoimmune disease. There was evidence of aluminium, cadmium and lead intoxication in a 63-year old Italian woman affected by rheumatoid arthritis (RA). We treated the patient with calcium disodium edetate (EDTA) once a week for a year in order to remove traces of heavy metal intoxication. Oxidative status profile was carried out at the beginning and after 6 months' EDTA chelation. At the end of the treatment, the patient did not show any signs of metal intoxication, RA symptoms and oxidative status improved.

Metal chelation therapy in rheumathoid arthritis : a case report. Successful management of rheumathoid arthritis by metal chelation therapy / F. Bamonti, A. Fulgenzi, C. Novembrino, M.E. Ferrero. - In: BIOMETALS. - ISSN 0966-0844. - 24:6(2011 Dec), pp. 1093-1098.

Metal chelation therapy in rheumathoid arthritis : a case report. Successful management of rheumathoid arthritis by metal chelation therapy

F. Bamonti
Primo
;
A. Fulgenzi
Secondo
;
C. Novembrino
Penultimo
;
M.E. Ferrero
Ultimo
2011

Abstract

Toxic metals are involved in the pathogenesis of some neurodegenerative and vascular diseases and are known to impair the immune system functions. We report here the case of a patient affected by heavy metal intoxication, who had developed an autoimmune disease. There was evidence of aluminium, cadmium and lead intoxication in a 63-year old Italian woman affected by rheumatoid arthritis (RA). We treated the patient with calcium disodium edetate (EDTA) once a week for a year in order to remove traces of heavy metal intoxication. Oxidative status profile was carried out at the beginning and after 6 months' EDTA chelation. At the end of the treatment, the patient did not show any signs of metal intoxication, RA symptoms and oxidative status improved.
Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica
Settore MED/04 - Patologia Generale
dic-2011
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/171080
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