Purpose: To study the safety and efficacy of T-Clair SPHP700-3, a new over-the-counter preservative-free formulation, in the management of mild to moderate dry eye in adults. Methods: Sixty adult patients with mild to moderate dry eye were consecutively recruited in 2 eye clinics and randomized into 2 groups: treatment and placebo. Signs and symptoms of dry eye were compared along 28 days of treatment. Results: No adverse events were reported during the study. Symptoms and signs of dry eye showed significant differences between the 2 groups after 2 and 4 weeks of treatment. Conclusions: SPHP700-3 preservative-free formulation showed to be safe and effective in mild to moderate dry eye, improving tear film stability, ocular surface lubrification, and patients' symptomatology. Copyright
A multicenter, double-blind, parallel group, placebo-controlled clinical study to examine the safety and efficacy of T-Clair SPHP700-3 in the management of mild to moderate dry eye in adults / E. Villani, G. Laganovska, F. Viola, C. Pirondini, K. Baumane, L. Radecka, R. Ratiglia. - In: CORNEA. - ISSN 0277-3740. - 30:3(2011), pp. 265-268.
Titolo: | A multicenter, double-blind, parallel group, placebo-controlled clinical study to examine the safety and efficacy of T-Clair SPHP700-3 in the management of mild to moderate dry eye in adults |
Autori: | VILLANI, EDOARDO (Primo) RATIGLIA, ROBERTO (Ultimo) |
Parole Chiave: | dry eye; ocular surface; over-the-counter eyedrops; preservative-free formulation |
Settore Scientifico Disciplinare: | Settore MED/30 - Malattie Apparato Visivo |
Data di pubblicazione: | 2011 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1097/ICO.0b013e3181e9aab8 |
Appare nelle tipologie: | 01 - Articolo su periodico |