The use of human stem cells in biomedical research projects is increasing steadily and the number of cells that are being derived develops at a remarkable pace. However, stem cells around the world are vastly different in their provenance, programming and potentials. Furthermore, knowledge on the actual number of cell types, their derivation, availability and characteristics is rather sparse. Usually, “colleague-supply” avenues constantly furnish cells to laboratories around the world without ensuring their correct identity, characterization and quality. These parameters are critical if the cells will be eventually used in toxicology studies and drug discovery. Here we outline some basic principles in establishing a stem cell specific bank.
The science of stem cell biobanking : investing in the future / G. Diaferia, M. Cardano, M. Cattaneo, C.C. Spinelli, S.S. Dessì, P. De Blasio, I. Biunno. - In: JOURNAL OF CELLULAR PHYSIOLOGY. - ISSN 0021-9541. - 227:1(2012 Jan), pp. 14-19.
The science of stem cell biobanking : investing in the future
G. DiaferiaPrimo
;M. CardanoSecondo
;C.C. Spinelli;
2012
Abstract
The use of human stem cells in biomedical research projects is increasing steadily and the number of cells that are being derived develops at a remarkable pace. However, stem cells around the world are vastly different in their provenance, programming and potentials. Furthermore, knowledge on the actual number of cell types, their derivation, availability and characteristics is rather sparse. Usually, “colleague-supply” avenues constantly furnish cells to laboratories around the world without ensuring their correct identity, characterization and quality. These parameters are critical if the cells will be eventually used in toxicology studies and drug discovery. Here we outline some basic principles in establishing a stem cell specific bank.Pubblicazioni consigliate
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