The aim of this case series is to histologically examine a new hydroxyapatite in sinus lift procedure after 3 months. Ten 2-stage sinus lifts were performed in 10 healthy patients having initial bone height of 1-2 mm and bone width of 5 mm, asking for a fixed implant-supported rehabilitation. After graft material augmentation, a rough-surfaced mini-implant was inserted to maintain stability of the sinus widow. A bioptical core containing a mini-implant was retrieved 3 months after maxillary sinus augmentation with NanoBone (R) and processed for undecalcified histology. From the histomorphometric analysis, NanoBone (R) residuals accounted for the 38.26%+/- 8.07% of the bioptical volume, marrow spaces for the 29.23%+/- 5.18% and bone for the 32.51%+/- 4.96% (new bone: 20.64%+/- 2.96%, native bone: 11.87%+/- 3.27%). Well-mineralized regenerated bone with lamellar parallel-fibred structure and Haversian systems surrounded the residual NanoBone (R) particles. The measured bone-to-implant contact amounted to 26.02%+/- 5.46%. No connective tissue was observed at the implant boundary surface. In conclusion, the tested material showed good histological outcomes also 3 months after surgery. In such critical conditions, the use of a rough-surfaced mini-implant showed BIC values supposed to be effective also in case of functional loading. Although longer follow-up and a wider patient size are needed, these preliminary results encourage further research on this biomaterial for implant load also under early stage and critical conditions.

Maxillary sinus floor augmentation using a nano-crystalline hydroxyapatite silica gel : case series and 3-month preliminary histological results / C. Canullo, C. Dellavia, F. Heinemann. - In: ANNALS OF ANATOMY. - ISSN 0940-9602. - 194:2(2012 Mar 20), pp. 174-178.

Maxillary sinus floor augmentation using a nano-crystalline hydroxyapatite silica gel : case series and 3-month preliminary histological results

C. Dellavia;
2012

Abstract

The aim of this case series is to histologically examine a new hydroxyapatite in sinus lift procedure after 3 months. Ten 2-stage sinus lifts were performed in 10 healthy patients having initial bone height of 1-2 mm and bone width of 5 mm, asking for a fixed implant-supported rehabilitation. After graft material augmentation, a rough-surfaced mini-implant was inserted to maintain stability of the sinus widow. A bioptical core containing a mini-implant was retrieved 3 months after maxillary sinus augmentation with NanoBone (R) and processed for undecalcified histology. From the histomorphometric analysis, NanoBone (R) residuals accounted for the 38.26%+/- 8.07% of the bioptical volume, marrow spaces for the 29.23%+/- 5.18% and bone for the 32.51%+/- 4.96% (new bone: 20.64%+/- 2.96%, native bone: 11.87%+/- 3.27%). Well-mineralized regenerated bone with lamellar parallel-fibred structure and Haversian systems surrounded the residual NanoBone (R) particles. The measured bone-to-implant contact amounted to 26.02%+/- 5.46%. No connective tissue was observed at the implant boundary surface. In conclusion, the tested material showed good histological outcomes also 3 months after surgery. In such critical conditions, the use of a rough-surfaced mini-implant showed BIC values supposed to be effective also in case of functional loading. Although longer follow-up and a wider patient size are needed, these preliminary results encourage further research on this biomaterial for implant load also under early stage and critical conditions.
bone regeneration; maxillary sinus floor augmentation; nano-crystalline hydroxyapatite
Settore BIO/16 - Anatomia Umana
Settore BIO/17 - Istologia
Settore MED/28 - Malattie Odontostomatologiche
Settore MED/29 - Chirurgia Maxillofacciale
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/167241
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