ARDS does not homogeneously affect the lung parenchyma and the infiltrates visible at the chest X-ray may derive from atelectasis, interstitial or intra-acinar edema or consolidation.. The lung injury severity is widely distributed in ARDS population (5 to 70% of the total lung weight) and it is strictly associated with the severity of injury: greater is the amount of gasless tissue at 5 cmH2O PEEP, greater is the amount of gasless tissue regaining aeration at 45 cmH2O airway pressure. We hypothesized that the regions that experience the major amount of stress and strain during mechanical ventilation are the region near to the always closed ones.
Lung dishomogeneity in ARDS / L. Gattinoni. ((Intervento presentato al convegno Workshop on Traslational Research in Lung Biology tenutosi a Madrid nel 2011.
Lung dishomogeneity in ARDS
L. GattinoniPrimo
2011
Abstract
ARDS does not homogeneously affect the lung parenchyma and the infiltrates visible at the chest X-ray may derive from atelectasis, interstitial or intra-acinar edema or consolidation.. The lung injury severity is widely distributed in ARDS population (5 to 70% of the total lung weight) and it is strictly associated with the severity of injury: greater is the amount of gasless tissue at 5 cmH2O PEEP, greater is the amount of gasless tissue regaining aeration at 45 cmH2O airway pressure. We hypothesized that the regions that experience the major amount of stress and strain during mechanical ventilation are the region near to the always closed ones.
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