The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed.

Recurrent leishmaniasis in kidney transplant recipients : report of 2 cases and systematic review of the literature / I. Simon, K. M. Wissing, V. Del Marmol, S. Antinori, M. Remmelink, E. Nilufer Broeders, J. L. Nortier, M. Corbellino, D. Abramowicz, A. Cascio. - In: TRANSPLANT INFECTIOUS DISEASE. - ISSN 1398-2273. - 13:4(2011 Aug), pp. 397-406.

Recurrent leishmaniasis in kidney transplant recipients : report of 2 cases and systematic review of the literature

S. Antinori;
2011

Abstract

The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed.
Cryoglobulinemia; Leishmania; Leishmaniasis; Tongue; Transplant; Vasculitis
Settore MED/17 - Malattie Infettive
ago-2011
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/165065
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