Coag-A-Mate X2 (General Diagnostics) is an automated photo-optical system for detection of clots, which can be used for measuring prothrombin time (PT) and activated partial thromboplastin time (APTT) and assaying coagulation factors. We have compared results obtained with this instrument with those obtained by the manual method used routinely in our specialized laboratory. The instrumental results showed good precision (PT: between-assay CV from 1.3 to 3.0, APTT: from 2.2 to 3.1), and high degree of correlation with the manual results (for PT r = 0.99, for APTT r = 0.95). There was also good correlation between the two methods (0.98-0.99) for factor assays (V, VII, VIII, IX, X, XI, and XII). High output, reproducibility, comparability and flexibility make this instrument suitable for both clinical and research laboratories

Assessment of a new instrument (Coag-A-Mate X2) for performing global clotting tests and specific factor assays / M. Cugno, V. Chantarangkul, A. Tripodi, P. M. Mannucci. - In: CLINICAL AND LABORATORY HAEMATOLOGY. - ISSN 0141-9854. - 7:1(1985), pp. 75-81.

Assessment of a new instrument (Coag-A-Mate X2) for performing global clotting tests and specific factor assays

M. Cugno
Primo
;
A. Tripodi
Penultimo
;
P. M. Mannucci
Ultimo
1985

Abstract

Coag-A-Mate X2 (General Diagnostics) is an automated photo-optical system for detection of clots, which can be used for measuring prothrombin time (PT) and activated partial thromboplastin time (APTT) and assaying coagulation factors. We have compared results obtained with this instrument with those obtained by the manual method used routinely in our specialized laboratory. The instrumental results showed good precision (PT: between-assay CV from 1.3 to 3.0, APTT: from 2.2 to 3.1), and high degree of correlation with the manual results (for PT r = 0.99, for APTT r = 0.95). There was also good correlation between the two methods (0.98-0.99) for factor assays (V, VII, VIII, IX, X, XI, and XII). High output, reproducibility, comparability and flexibility make this instrument suitable for both clinical and research laboratories
Blood coagulation tests ; humans ; blood coagulation factors ; autoanalysis ; prothrombin time ; male ; female ; partial thromboplastin time
Settore MED/09 - Medicina Interna
1985
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/164003
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