Since L-Arginine is the substrate for nitric oxide synthesis by vascular endothelial cells the effects of L-arginine treatment on the digital vascular response to local stimuli were investigated in patients with primary or secondary Raynaud's phenomenon. After therapy, patients with Raynaud's phenomenon secondary to systemic sclerosis showed: (1) higher digital vasodilation after local warming, (2) cold-induced digital vasodilation, and (3) increase of plasma levels of tissue-type plasminogen activator

L-arginine therapy in Raynaud's phenomenon? / A. Agostoni, B. Marasini, M. L. Biondi, C. Bassani, A. Cazzaniga, B. Bottasso, M. Cugno. - In: INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH. - ISSN 0940-5437. - 21:2(1992), pp. 202-203.

L-arginine therapy in Raynaud's phenomenon?

A. Agostoni;B. Marasini;B. Bottasso;M. Cugno
1992

Abstract

Since L-Arginine is the substrate for nitric oxide synthesis by vascular endothelial cells the effects of L-arginine treatment on the digital vascular response to local stimuli were investigated in patients with primary or secondary Raynaud's phenomenon. After therapy, patients with Raynaud's phenomenon secondary to systemic sclerosis showed: (1) higher digital vasodilation after local warming, (2) cold-induced digital vasodilation, and (3) increase of plasma levels of tissue-type plasminogen activator
l-Arginine; Raynaud's phenomenon; Strain-gauge plethysmography; Systemic sclerosis; Tissue-type plasminogen activator
Settore MED/09 - Medicina Interna
INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH
http://www.ncbi.nlm.nih.gov/pubmed/1815764
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/162965
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 20
  • ???jsp.display-item.citation.isi??? 14
social impact