Monoacylglycosylglycerols show anti-tumor promoting effects: in order to study the role of the ester function we have prepared by simple methods (R)-1-O-benzyl-1,2-decandiol, (R)-3-O-benzyl-1-O-hexyl-sn-glycerol, and (R)-1-O-benzyl-5-oxo-1,2-decandiol; these optically active compounds are building blocks for the synthesis of monohexanoylglycosylglycerol isosters.
Novel chiral glycerol analogues building blocks. Application to the synthesis of bioactive glycoglycerolipid analogues / P. Ferraboschi, D. Colombo, F. Compostella, S. Reza Elahi. - In: SYNLETT. - ISSN 0936-5214. - 2001:9(2001), pp. 1379-1382. [10.1055/s-2001-16789]
Novel chiral glycerol analogues building blocks. Application to the synthesis of bioactive glycoglycerolipid analogues
P. Ferraboschi
Primo
;D. ColomboSecondo
;F. CompostellaPenultimo
;
2001
Abstract
Monoacylglycosylglycerols show anti-tumor promoting effects: in order to study the role of the ester function we have prepared by simple methods (R)-1-O-benzyl-1,2-decandiol, (R)-3-O-benzyl-1-O-hexyl-sn-glycerol, and (R)-1-O-benzyl-5-oxo-1,2-decandiol; these optically active compounds are building blocks for the synthesis of monohexanoylglycosylglycerol isosters.
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