Insulin resistance is a key factor in the pathogenesis of hepatogenous diabetes and influences the prognosis of chronic liver diseases. In vivo assessment of insulin resistance in humans is expensive; therefore, surrogate indices based on a fasting plasma glucose and insulin concentrations (HOMA-IS, QUICKI) were proposed. This study aimed to test whether these simple indices are reliable measures of insulin sensitivity in patients with liver cirrhosis before and after liver transplantation (LTx).
Assessment of insulin sensitivity based on a fasting blood sample in men with liver cirrhosis before and after liver transplantation / G. Perseghin, A. Caumo, V. Mazzaferro, A. Pulvirenti, L. Piceni Sereni, R. Romito, G. Lattuada, J.C. Coppa, F. Costantino, E. Regalia, L. Luzi. - In: TRANSPLANTATION. - ISSN 0041-1337. - 76:4(2003 Aug 27), pp. 697-702.
Assessment of insulin sensitivity based on a fasting blood sample in men with liver cirrhosis before and after liver transplantation
G. PerseghinPrimo
;A. CaumoSecondo
;V. Mazzaferro;G. Lattuada;J.C. Coppa;L. LuziUltimo
2003
Abstract
Insulin resistance is a key factor in the pathogenesis of hepatogenous diabetes and influences the prognosis of chronic liver diseases. In vivo assessment of insulin resistance in humans is expensive; therefore, surrogate indices based on a fasting plasma glucose and insulin concentrations (HOMA-IS, QUICKI) were proposed. This study aimed to test whether these simple indices are reliable measures of insulin sensitivity in patients with liver cirrhosis before and after liver transplantation (LTx).
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