A consortium of 20 university departments of geriatrics and gerontology conducted the Italian Multicentric Study on Centenarians (IMSC), in order to assess the socio-economic, clinical and biological conditions of the Italian centenarians. The investigation involved 382 subjects randomly selected from a total of 1162 centenarians (234 men and 928 women), recorded by a census carried out until 31 December, 1993. Their case history, clinical and socio-economic data were recorded on a computerized clinical case sheet. Blood samples for the purpose of the present investigations were drawn from 257 of them. A great proportion (79%) of these latter subjects displayed satisfactory general conditions in their laboratory parameters, 18.3% of them had fairly good clinical conditions even with slightly modified laboratory parameters. Only a low percentage (2.8%) had poor general conditions with a marked anemia, hyperazotemia and uric acid levels. Long duration diabetes was practically absent, and only 5.5% of our centenarians displayed hyperglycemia with a mean duration time of 9.3 years. The prevalence of subjects with hypercholesterolemia was 31.1%. Only 4.3% of centenarians was affected by mixed form of dyslipidemia (hypertriglyceridemia associated with hypercholesterolemia), confirming that elevated blood lipid contents jeopardize really long survival.
Laboratory parameters of italian centenarians / A. Capurso, A.M. Colacicco, V. Solfrizzi, A. Gaddi, S. Daddato, C. Galletti, M. Trabucchi, S. Boffelli, R. Rozzini, L. Motta, R. Rapisarda, R. Mattace, M. Motta, L. Pansini, G. Masotti, N. Marchionni, E. Petruzzi, S. Bertolini, M. Agretti, P. Costelli, D. Mari, F. Duca, P. Ferrazzi, E. Bosi, M. Manzoni, A. Franzone. - In: ARCHIVES OF GERONTOLOGY AND GERIATRICS. - ISSN 0167-4943. - 27:1(1998), pp. 67-74. [10.1016/S0167-4943(98)00100-9]
Laboratory parameters of italian centenarians
D. Mari;
1998
Abstract
A consortium of 20 university departments of geriatrics and gerontology conducted the Italian Multicentric Study on Centenarians (IMSC), in order to assess the socio-economic, clinical and biological conditions of the Italian centenarians. The investigation involved 382 subjects randomly selected from a total of 1162 centenarians (234 men and 928 women), recorded by a census carried out until 31 December, 1993. Their case history, clinical and socio-economic data were recorded on a computerized clinical case sheet. Blood samples for the purpose of the present investigations were drawn from 257 of them. A great proportion (79%) of these latter subjects displayed satisfactory general conditions in their laboratory parameters, 18.3% of them had fairly good clinical conditions even with slightly modified laboratory parameters. Only a low percentage (2.8%) had poor general conditions with a marked anemia, hyperazotemia and uric acid levels. Long duration diabetes was practically absent, and only 5.5% of our centenarians displayed hyperglycemia with a mean duration time of 9.3 years. The prevalence of subjects with hypercholesterolemia was 31.1%. Only 4.3% of centenarians was affected by mixed form of dyslipidemia (hypertriglyceridemia associated with hypercholesterolemia), confirming that elevated blood lipid contents jeopardize really long survival.File | Dimensione | Formato | |
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