Clinical studies on the effect of growth hormone (GH) on thyroid function in patients with GH deficiency are contradictory. Further, the majority of published observations are limited to the first 6-12 months of GH replacement therapy. The aim of our study was to estimate the incidence of clinically relevant hypothyroidism in a cohort of patients with adult GH deficiency (AGHD) during long-term therapy with recombinant human GH (rhGH).

Long-term effects of growth hormone replacement therapy on thyroid function in adults with growth hormone deficiency / M. Losa, M. Scavini, E. Gatti, A. Rossini, S. Madaschi, I. Formenti, A. Caumo, C. A. Stidley, R. Lanzi. - In: THYROID. - ISSN 1050-7256. - 18:12(2008 Dec), pp. 1249-1254.

Long-term effects of growth hormone replacement therapy on thyroid function in adults with growth hormone deficiency

A. Caumo;
2008

Abstract

Clinical studies on the effect of growth hormone (GH) on thyroid function in patients with GH deficiency are contradictory. Further, the majority of published observations are limited to the first 6-12 months of GH replacement therapy. The aim of our study was to estimate the incidence of clinically relevant hypothyroidism in a cohort of patients with adult GH deficiency (AGHD) during long-term therapy with recombinant human GH (rhGH).
Hormone Replacement Therapy. ; Human Growth Hormone ; Recombinant Proteins; Humans ; Retrospective Studies ; Child; Dwarfism, Pituitary ; Thyroid Gland ; Adult ; Thyroxine; Hypothyroidism ; Incidence ; Follow-Up Studies. '; Middle Aged. ; Female ; Male
Settore ING-INF/06 - Bioingegneria Elettronica e Informatica
dic-2008
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/160270
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