Studies have pointed to insulin resistance as a pathogenic factor in fatty liver. Although pancreatic B-cell function is believed to be involved, its role is unclear. This study was undertaken to test whether fasting C-peptide, an index of fasting B-cell function, was related to intra-hepatic fat (IHF) content in non-diabetic humans.
Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance / G. Perseghin, A. Caumo, G. Lattuada, F. De Cobelli, G. Natali, A. Esposito, E. Belloni, T. Canu, F. Ragogna, P. Scifo, A. Del Maschio, L. Luzi. - In: DIABETIC MEDICINE. - ISSN 0742-3071. - 26:9(2009 Sep), pp. 847-854.
Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance
G. PerseghinPrimo
;A. CaumoSecondo
;L. LuziUltimo
2009
Abstract
Studies have pointed to insulin resistance as a pathogenic factor in fatty liver. Although pancreatic B-cell function is believed to be involved, its role is unclear. This study was undertaken to test whether fasting C-peptide, an index of fasting B-cell function, was related to intra-hepatic fat (IHF) content in non-diabetic humans.
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