Studies have pointed to insulin resistance as a pathogenic factor in fatty liver. Although pancreatic B-cell function is believed to be involved, its role is unclear. This study was undertaken to test whether fasting C-peptide, an index of fasting B-cell function, was related to intra-hepatic fat (IHF) content in non-diabetic humans.

Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance / G. Perseghin, A. Caumo, G. Lattuada, F. De Cobelli, G. Natali, A. Esposito, E. Belloni, T. Canu, F. Ragogna, P. Scifo, A. Del Maschio, L. Luzi. - In: DIABETIC MEDICINE. - ISSN 0742-3071. - 26:9(2009 Sep), pp. 847-854.

Elevated fasting plasma C-peptide occurs in non-diabetic individuals with fatty liver, irrespective of insulin resistance

G. Perseghin
Primo
;
A. Caumo
Secondo
;
L. Luzi
Ultimo
2009

Abstract

Studies have pointed to insulin resistance as a pathogenic factor in fatty liver. Although pancreatic B-cell function is believed to be involved, its role is unclear. This study was undertaken to test whether fasting C-peptide, an index of fasting B-cell function, was related to intra-hepatic fat (IHF) content in non-diabetic humans.
Free fatty acids; Homeostasis model assessment; Intra-hepatic fat; Magnetic resonance spectroscopy
Settore MED/50 - Scienze Tecniche Mediche Applicate
Settore ING-INF/06 - Bioingegneria Elettronica e Informatica
Settore MED/13 - Endocrinologia
set-2009
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/160269
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