We reviewed the main disturbances of hemostasis (coagulation, platelet, fibrinolysis) occurring in acute and chronic liver disease and during cholestasis. The significance of coagulation testing in the evaluation of hepatocytic synthetic function and the value of these tests in predicting bleeding episodes are also discussed in detail. Finally the role of replacement therapy with fresh-frozen plasma and prothrombin complex concentrates is evaluated for the treatment of bleeding occurring during various types of liver disease.
|Titolo:||Hemostasis and liver disease|
MARI, DANIELA (Primo)
MANNUCCI, PIER MANNUCCIO (Ultimo)
|Settore Scientifico Disciplinare:||Settore MED/09 - Medicina Interna|
|Data di pubblicazione:||1981|
|Appare nelle tipologie:||01 - Articolo su periodico|