We reviewed the main disturbances of hemostasis (coagulation, platelet, fibrinolysis) occurring in acute and chronic liver disease and during cholestasis. The significance of coagulation testing in the evaluation of hepatocytic synthetic function and the value of these tests in predicting bleeding episodes are also discussed in detail. Finally the role of replacement therapy with fresh-frozen plasma and prothrombin complex concentrates is evaluated for the treatment of bleeding occurring during various types of liver disease.
Hemostasis and liver disease / D. Mari, P.M. Mannucci. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 66:2(1981), pp. 233-248.
Hemostasis and liver disease
D. MariPrimo
;P.M. MannucciUltimo
1981
Abstract
We reviewed the main disturbances of hemostasis (coagulation, platelet, fibrinolysis) occurring in acute and chronic liver disease and during cholestasis. The significance of coagulation testing in the evaluation of hepatocytic synthetic function and the value of these tests in predicting bleeding episodes are also discussed in detail. Finally the role of replacement therapy with fresh-frozen plasma and prothrombin complex concentrates is evaluated for the treatment of bleeding occurring during various types of liver disease.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Hemostasis and liver disease.pdf
accesso aperto
Tipologia:
Publisher's version/PDF
Dimensione
3.36 MB
Formato
Adobe PDF
|
3.36 MB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
