The authors report the presence of high titer antibodies to glutamic acid decarboxylase (anti-GAD65) until age 24 months in two asymptomatic newborns of a woman with stiff-person syndrome (SPS). No signs of SPS were detectable in the two children at ages 6 and 8 years. This observation indicates that other cofactors are involved in the pathogenesis of SPS.
Stiff person syndrome does not always occur with maternal passive transfer of GAD65 antibodies / R. Nemni, L.M. Caniatti, M. Gironi, E. Bazzigaluppi, D. De Grandis. - In: NEUROLOGY. - ISSN 0028-3878. - 62:11(2004), pp. 2101-2102. [10.1212/01.WNL.0000127446.61806.2F]
Stiff person syndrome does not always occur with maternal passive transfer of GAD65 antibodies
R. NemniPrimo
;
2004
Abstract
The authors report the presence of high titer antibodies to glutamic acid decarboxylase (anti-GAD65) until age 24 months in two asymptomatic newborns of a woman with stiff-person syndrome (SPS). No signs of SPS were detectable in the two children at ages 6 and 8 years. This observation indicates that other cofactors are involved in the pathogenesis of SPS.
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