Molecular genetics has strongly influenced clinical medicine and particularly nephrology. Several gene mutations of single-gene hereditary nephropathies have been recently identified. These data are useful to develop methods of diagnosis and treatment, but also to understand the pathogenesis of these particular disorders. In this review we focused on several monogenic hereditary renal diseases inducing nephrotic syndrome and other hereditary diseases with renal involvement and progression towards end-stage renal failure.
|Titolo:||Glomerular changes in hereditary single-gene diseases|
|Parole Chiave:||Congenital nephrotic syndrome; Hereditary glomerulonephritis; Molecular genetics; Monogenic hereditary nephropathy|
|Settore Scientifico Disciplinare:||Settore MED/08 - Anatomia Patologica|
|Data di pubblicazione:||2002|
|Appare nelle tipologie:||01 - Articolo su periodico|