The radionuclide production for biomedical applications has been brought up in the years, as a special nuclear application, at INFN LASA Laboratory, particularly in co-operation with the JRC-Ispra of EC. Mainly scientific aspects concerning radiation detection and the relevant instruments, the measurements of excitation functions of the involved nuclear reactions, the requested radiochemistry studies and further applications have been investigated. On the side of the nuclear data evaluations, based on nuclear model calculations and critically selected experimental data, the appropriate competence has been developed at ENEA Division for Advanced Physics Technologies. A series of high specific activity accelerator-produced radionuclides in no-carrier-added (NCA) form, for uses in metabolic radiotherapy and for PET radiodiagnostics, are investigated. In this work, last revised measurements and model calculations are reviewed for excitation functions of natZn(d,X) 64Cu, 66Ga reactions, referring to irradiation experiments at K=38 variable energy Cyclotron of JRC-Ispra. Concerning the reaction data for producing 186gRe and 211At/ 211gPo (including significant emission spectra) and 210At, most recent and critically selected experimental results are considered and discussed in comparison with model calculations paying special care to pre-equilibrium effects estimate and to the appropriate overall parameterization. Model calculations are presented for 226Ra(p,2n) 225Ac reaction, according to the working program of the ongoing IAEA CRP on the matter.
|Titolo:||Comparison between theoretical calculation and experimental results of excitation functions for production of relevant biomedical radionuclides|
|Autori interni:||GROPPI GARLANDINI, FLAVIA MARIA|
BIRATTARI, CLAUDIO CARMELO (Secondo)
MORZENTI, SABRINA (Penultimo)
|Parole Chiave:||funzioni d'eccitazione; produzione di radioisotopi a scopo biomedico; rivelatori di radiazioni; reazioni nucleari; separazioni radiochimiche; modelli nucleari; No Carrier Added; radioterapia metabolica; radiodiagnostica PET; natZn(d,X)64Cu; natZn(d,X)66Ga; 186gRe; 211At; 211gPo; 210At; 226Ra(p,2n)225Ac; spettrometria gamma; spettrometria alfa|
|Settore Scientifico Disciplinare:||Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)|
Settore CHIM/03 - Chimica Generale e Inorganica
|Data di pubblicazione:||2005|
|Digital Object Identifier (DOI):||10.1063/1.1945321|
|Tipologia:||Book Part (author)|
|Appare nelle tipologie:||03 - Contributo in volume|
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