The prepn. of dendrons of α(1,2)α(1,6)pseudomannotrioses is presented for the treatment and/or prevention of HIV; Ebola, Dengue, Hepatitis C, SARS or tuberculosis infections. Specifically, a third generation bis(methoxyol)propanoic based dendrimer bearing α(1,2)α(1,6)pseudomannotriose was prepd. and tested on HIV viral strains and showed >99% inhibition at 50μM.
Inhibitors of microbial infections / A. Bernardi, S. Sattin, M.S. Clerici, A.M.V. Berzi, F.J. Rojo, M. Sanchez, J.J. Reina, F. Fieschi.
Inhibitors of microbial infections
A. BernardiPrimo
;S. SattinSecondo
;M.S. Clerici;A.M.V. Berzi;J.J. ReinaPenultimo
;
2011
Abstract
The prepn. of dendrons of α(1,2)α(1,6)pseudomannotrioses is presented for the treatment and/or prevention of HIV; Ebola, Dengue, Hepatitis C, SARS or tuberculosis infections. Specifically, a third generation bis(methoxyol)propanoic based dendrimer bearing α(1,2)α(1,6)pseudomannotriose was prepd. and tested on HIV viral strains and showed >99% inhibition at 50μM.
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