In some patients, Campylobacter jejuni infection has been associated with the development of multifocal motor neuropathy (MMN) and high titers of antiganglioside antibodies. The authors measured anti-C. jejuni antibodies by ELISA and immunoblot in 20 patients with MMN, and correlated their presence with antiganglioside reactivity and a history of recent diarrhea. Only one patient had high titers of anti-C. jejuni antibodies, indicating that C. jejuni is unlikely to be involved in the pathogenesis of MMN in most patients
Multifocal motor neuropathy and Campylobacter jejuni reactivity / F. Terenghi, S. Allaria, G. Scarlato, E. Nobile-Orazio. - In: NEUROLOGY. - ISSN 0028-3878. - 59:2(2002), pp. 282-284.
Multifocal motor neuropathy and Campylobacter jejuni reactivity
G. ScarlatoPenultimo
;E. Nobile-OrazioUltimo
2002
Abstract
In some patients, Campylobacter jejuni infection has been associated with the development of multifocal motor neuropathy (MMN) and high titers of antiganglioside antibodies. The authors measured anti-C. jejuni antibodies by ELISA and immunoblot in 20 patients with MMN, and correlated their presence with antiganglioside reactivity and a history of recent diarrhea. Only one patient had high titers of anti-C. jejuni antibodies, indicating that C. jejuni is unlikely to be involved in the pathogenesis of MMN in most patients
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