The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and non-ADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 person-years of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM.
The incidence of malignancies in HIV-infected patients and prognostic role of current CD4 cell count : evidence from a large Italian cohort study / M.C. Prosperi, A. Cozzi-Lepri, A. Castagna, C. Mussini, R. Murri, A. Giacometti, C. Torti, A. Costantini, P. Narciso, F. Ghinelli, A. Antinori, A. d'Arminio Monforte, Icona Foundation Study Group. - In: CLINICAL INFECTIOUS DISEASES. - ISSN 1058-4838. - 50:9(2010 May 01), pp. 1316-1321. [10.1086/651688]
The incidence of malignancies in HIV-infected patients and prognostic role of current CD4 cell count : evidence from a large Italian cohort study
A. d'Arminio MonfortePenultimo
;
2010
Abstract
The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and non-ADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 person-years of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM.
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