Raltegravir (RAL), an HIV integrase inhibitor, may uncommonly induce an increase of serum creatine kinase (CK) both in naïve and antiretroviral (ARV)-experienced HIV-positive patients. We report the case of severe rhabdomyolysis requiring hospitalization in an ARV-experienced HIV/hepatitis C co-infected patient treated with a RAL-containing drug regimen. Factors favouring a severe clinical occurrence of RAL-induced rhabdomyolysis from cases reported in literature are described.
Severe raltegravir-associated rhabdomyolysis: a case report and review of the literature / F. Croce, P. Vitiello, A. Dalla Pria, A. Riva, M. Galli, S. Antinori. - In: INTERNATIONAL JOURNAL OF STD & AIDS. - ISSN 0956-4624. - 21:11(2010), pp. 783-785.
Titolo: | Severe raltegravir-associated rhabdomyolysis: a case report and review of the literature |
Autori: | CROCE, FRANCESCO GIULIO (Primo) VITIELLO, PAOLA (Secondo) GALLI, MASSIMO (Penultimo) ANTINORI, SPINELLO (Ultimo) |
Parole Chiave: | Antiretroviral treatment; HIV; Raltegravir; Rhabdomyolysis |
Settore Scientifico Disciplinare: | Settore MED/17 - Malattie Infettive |
Data di pubblicazione: | 2010 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1258/ijsa.2010.010246 |
Appare nelle tipologie: | 01 - Articolo su periodico |