The interaction between the presence of a subendocardial ischemic region and the anisotropic structure of the cardiac muscle is investigated here by means of numerical simulations based on the anisotropic Monodomain and Bidomain models. Extracellular potential distributions during the ST and TQ intervals are computed separately using these nonstationary models. During the ST interval, the extracellular potential patterns differ from those simulated with stationary models used in the literature. These differences are explained by decomposing the cardiac current sources into conormal, axial and orthogonal components and determining which component is dominant during the ST and TQ intervals.

Anisotropic dynamical modeling of the mechanism of ST and TQ segment changes during subendocardial ischemia / P. Colli Franzone, L.F. Pavarino, S. Scacchi - In: World congress on medical physics and biomedical engineering / [a cura di] O. Dössel, W. C. Schlegel. - [s.l] : Springer, 2009. - pp. 462-465 (( convegno World Congress on Medical Physics and Biomedical Engineering tenutosi a Munich, Germany nel 2009 [10.1007/978-3-642-03879-2_130].

Anisotropic dynamical modeling of the mechanism of ST and TQ segment changes during subendocardial ischemia

L.F. Pavarino
Secondo
;
S. Scacchi
Ultimo
2009

Abstract

The interaction between the presence of a subendocardial ischemic region and the anisotropic structure of the cardiac muscle is investigated here by means of numerical simulations based on the anisotropic Monodomain and Bidomain models. Extracellular potential distributions during the ST and TQ intervals are computed separately using these nonstationary models. During the ST interval, the extracellular potential patterns differ from those simulated with stationary models used in the literature. These differences are explained by decomposing the cardiac current sources into conormal, axial and orthogonal components and determining which component is dominant during the ST and TQ intervals.
Monodomain and Bidomain models ; myocardial ischemia ; ST - TQ segment ; parallel simulations
Settore MAT/08 - Analisi Numerica
Book Part (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/151078
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