Determinazione della concentrazione sierica di Troponina cardiaca I in cavalli trottatori prima e dopo esercizio massimale su treadmill

The evaluation of the cardiac Troponin I (cTnI) serum or plasma concentration was recently introduced in the veterinary medicine as a sensible and specific marker of myocardial damage. In the literature are available data regarding the cTnI normal value in horses at rest and after exercise, in athletic and in pastured horses, as well as the identification of the main cardiac diseases that may cause an increased cTnI serum concentration. Aim of the present paper is to determine the cTnI serum concentration in a homogeneous population of standardbred horses in training and to evaluate the significance of different cTnI concentrations before and after strenuous exercise. The mean cTnI serum value at rest was 0.01 ng/ml (range 0-0.05 ng/ml); the mean cTnI serum value 6 hours after strenuous exercise on treadmill was 0.09 ng/ml (range 0.01-0.36 ng/ml); the mean cTnI serum value 24 hours after strenuous exercise on treadmill was 0.05 ng/ml (range 0-0.22 ng/ml). There were no statistically significant differences between cTnI serum concentrations obtained before, 6 hours and 24 hours after the treadmill test, although an increased cTnI serum concentration was observed in horses 6 hours after treadmill exercise. Furthermore, no statistically significant correlation was found between cTnI concentrations before and after exercise and exercise intensity, sex and age of the horses.

La determinazione della concentrazione sierica o plasmatica della Troponina cardiaca I è stata introdotta anche in medicina veterinaria quale marker di danno miocardico. Scopo del lavoro è quello di determinare la concentrazione sierica di cTnI in una popolazione omogenea di cavalli trottatori da corsa in allenamento e valutare le possibili variazioni di dosaggio di cTnI a riposo e dopo esercizio massimale.