The depression symptoms in the elderly may accompany mild cognitive impairment. The aim of this study was to evaluate the role of depression on the risk of evolving to Alzheimer disease (AD) among mild cognitive impairment (MCI) subjects. We present the results of a clinical study of 169 MCI. Diagnosis of depression was based on clinical criteria. The endpoint was development of AD. Result: 81 MCI subjetcs conversion in AD, MCI depressed subjects had reduced risck of conversion.
IMPATTO DELLA DEPRESSIONE SUL RISCHIO DI PROGRESSIONE DEL MILD COGNITIVE IMPAIRMENT A MALATTIA DI ALZHEIMER / S.m. Fusari Imperatori ; relatore: Claudio Mariani ; correlatore: Francesca Clerici. Università degli Studi di Milano, 2010 Dec 03. 23. ciclo, Anno Accademico 2010. [10.13130/fusari-imperatori-susanna-maria_phd2010-12-03].
IMPATTO DELLA DEPRESSIONE SUL RISCHIO DI PROGRESSIONE DEL MILD COGNITIVE IMPAIRMENT A MALATTIA DI ALZHEIMER
S.M. FUSARI IMPERATORI
2010
Abstract
The depression symptoms in the elderly may accompany mild cognitive impairment. The aim of this study was to evaluate the role of depression on the risk of evolving to Alzheimer disease (AD) among mild cognitive impairment (MCI) subjects. We present the results of a clinical study of 169 MCI. Diagnosis of depression was based on clinical criteria. The endpoint was development of AD. Result: 81 MCI subjetcs conversion in AD, MCI depressed subjects had reduced risck of conversion.
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