Following a request from the European Commission, the European Food Safety Authority (EFSA) was asked to consider additional data provided by the applicant subsequent to the previous opinion from the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). In its former opinion, the Panel could not conclude on the safety of manganese (Mn) from MintrexMn for the consumer because of the lack of data on Mn deposition in edible tissues. Data on tissue deposition has now been provided for chickens for fattening. In a 35-day experiment with chickens for fattening the Mn retention from MintrexMn was measured in liver, kidney, muscle, skin and fat in comparison to Mn sulphate and in relation to two supplementation levels (60 and 150 mg Mn/kg feed). There was no evidence for differences in Mn-concentrations in tissues of chickens for fattening fed Mn at two different supplementation levels and from the two Mn sources. The FEEDAP Panel concluded that MintrexMn would not increase Mn deposition in edible tissues of chickens for fattening compared to other authorised inorganic Mn sources for which it would substitute. Consequently, the use of MintrexMn as a feed additive for chickens for fattening is unlikely to present a safety concern to consumers.

Scientific opinion on consumer safety of a manganese chelate of hydroxy analogue of methionine (Mintrex®Mn) as feed additive for chickens for fattening / E. Panel on Additives, P. or Substances used in Animal Feed, G. Aquilina, G. Bories, P. Brantom, F. Caloni, A. Chesson, P.S. Cocconcelli, J. de Knecht, N.A. Dierick, M.A. Gralak, J. Gropp, I. Halle, N.G. Ilbäck, R. Kroker, L. Leng, S. Lindgren, A.K. Lundebye Haldorsen, A. Mantovani, M. Mézes, D. Renshaw, M. Saarela. - In: EFSA JOURNAL. - ISSN 1831-4732. - 7:9, art. 1316(2009), pp. 1-5. [10.2903/j.efsa.2009.1316]

Scientific opinion on consumer safety of a manganese chelate of hydroxy analogue of methionine (Mintrex®Mn) as feed additive for chickens for fattening

F. Caloni;
2009

Abstract

Following a request from the European Commission, the European Food Safety Authority (EFSA) was asked to consider additional data provided by the applicant subsequent to the previous opinion from the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP). In its former opinion, the Panel could not conclude on the safety of manganese (Mn) from MintrexMn for the consumer because of the lack of data on Mn deposition in edible tissues. Data on tissue deposition has now been provided for chickens for fattening. In a 35-day experiment with chickens for fattening the Mn retention from MintrexMn was measured in liver, kidney, muscle, skin and fat in comparison to Mn sulphate and in relation to two supplementation levels (60 and 150 mg Mn/kg feed). There was no evidence for differences in Mn-concentrations in tissues of chickens for fattening fed Mn at two different supplementation levels and from the two Mn sources. The FEEDAP Panel concluded that MintrexMn would not increase Mn deposition in edible tissues of chickens for fattening compared to other authorised inorganic Mn sources for which it would substitute. Consequently, the use of MintrexMn as a feed additive for chickens for fattening is unlikely to present a safety concern to consumers.
nutritional additive ; trace element ; manganese ; safety for the consumer ; chickens for fattening ; tissue deposition
Settore VET/07 - Farmacologia e Tossicologia Veterinaria
2009
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/150021
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