Objective The homocysteine level is considered an important cardiocerebral risk factor. Our aim was to investigate the impact of endurance training on the homocysteine cycle in élite and non-élite athletes. Methods The level of physical activity was measured using a SenseWear armband in five healthy marathon runners. Two blood samples, the first under basal conditions and the second after running a half marathon, were obtained in all subjects by venepuncture. Biochemical parameters, including total homocysteine levels, were assessed. Results Armband data indicated that each athlete ran the half marathon keeping a race pace close to their anaerobic threshold speed. Although the run times were very different between élite and non-élite athletes, a statistically significant increase in plasma homocysteine levels (p=0.026) was observed in all runners. Conclusion Endurance training for 75–100 min held at a race pace close to the anaerobic threshold speed induces an increase in serum plasma homocysteine level.
|Titolo:||Increase of homocysteine level after half-marathon running : a detrimental metabolic effect of sport?|
|Parole Chiave:||homocysteine ; marathon ; endurance ; diabetes ; physical activity|
|Settore Scientifico Disciplinare:||Settore M-EDF/02 - Metodi e Didattiche delle Attivita' Sportive|
|Data di pubblicazione:||ago-2010|
|Digital Object Identifier (DOI):||10.1007/s11332-010-0094-6|
|Appare nelle tipologie:||01 - Articolo su periodico|