Both type 1 (DMT1) and type 2 (DMT2) diabetes mellitus are characterized by the slow loss of the insulin-producing beta cells in the pancreas and by a long preclinical stage when diagnosis and preventive therapies are already possible. Our inventors identified a novel DMT1 auto-antigen which is selectively expressed by beta cells and likely involved in the control of their progressive death. The identified molecules represent novel targets or tools for the development of diagnostic tests and cytoprotective therapies for diabetes mellitus.

Methods and compositions for the diagnosis and treatment of diabetes / C. Perego, E.S. Di Cairano, A. Davalli, F. Folli.

Methods and compositions for the diagnosis and treatment of diabetes

C. Perego
Primo
;
E.S. Di Cairano
Secondo
;
F. Folli
2010-05-27

Abstract

Both type 1 (DMT1) and type 2 (DMT2) diabetes mellitus are characterized by the slow loss of the insulin-producing beta cells in the pancreas and by a long preclinical stage when diagnosis and preventive therapies are already possible. Our inventors identified a novel DMT1 auto-antigen which is selectively expressed by beta cells and likely involved in the control of their progressive death. The identified molecules represent novel targets or tools for the development of diagnostic tests and cytoprotective therapies for diabetes mellitus.
Università degli Studi di Milano
Fondazione Centro San Raffaele Del Monte Tabor
WO2010/057647
PCT/EP2009/008256
Settore BIO/09 - Fisiologia
Settore MED/13 - Endocrinologia
http://v3.espacenet.com/publicationDetails/originalDocument?CC=WO&NR=2010057647A2&KC=A2&FT=D&date=20100527&DB=EPODOC&locale=en_EP
Methods and compositions for the diagnosis and treatment of diabetes / C. Perego, E.S. Di Cairano, A. Davalli, F. Folli.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/147044
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