Extracorporeal membrane oxygenation (ECMO) is the only therapeutic option for patients with ventilation-refractory hypercapnia while awaiting lung transplantation. Moreover, there is increasing success using ECMO for definitive respiratory failure in formerly healthy patients. This report describes the use of membrane oxygenation as a bridge to lung transplantation in 2 patients on the waiting list and in 2 previously healthy patients. Our experience showed that coagulation management, critical illness myopathy, and psychological disorders were the most critical problems. One patient died at 2 days after transplantation, 1 at 3 months, and 2 returned to their pretransplantation activities. We concluded that ECMO is an adequate bridge to lung transplantation but, especially in formerly healthy patients, an awake procedure is advisable for a successful outcome.

Bridge to lung transplantation by venovenous extracorporeal membrane oxygenation : a lesson learned on the first four cases / M. Nosotti, L. Rosso, A. Palleschi, A. Lissoni, S. Crotti, C. Marenghi, C. Colombo, D. Costantini, L. Santambrogio. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 42:4(2010 May), pp. 1259-1261. ((Intervento presentato al convegno Congress of the Italian-Tranplantation-Society tenutosi a Milano nel 2009 [10.1016/j.transproceed.2010.03.119].

Bridge to lung transplantation by venovenous extracorporeal membrane oxygenation : a lesson learned on the first four cases

M. Nosotti;L. Rosso;A. Palleschi;C. Colombo;D. Costantini;L. Santambrogio
2010-05

Abstract

Extracorporeal membrane oxygenation (ECMO) is the only therapeutic option for patients with ventilation-refractory hypercapnia while awaiting lung transplantation. Moreover, there is increasing success using ECMO for definitive respiratory failure in formerly healthy patients. This report describes the use of membrane oxygenation as a bridge to lung transplantation in 2 patients on the waiting list and in 2 previously healthy patients. Our experience showed that coagulation management, critical illness myopathy, and psychological disorders were the most critical problems. One patient died at 2 days after transplantation, 1 at 3 months, and 2 returned to their pretransplantation activities. We concluded that ECMO is an adequate bridge to lung transplantation but, especially in formerly healthy patients, an awake procedure is advisable for a successful outcome.
Settore MED/21 - Chirurgia Toracica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/146767
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